Work experience students visit to the QUOD hub lab

In July 2024, QUOD teamed up with the Transplant Research Group at the University of Oxford to welcome students visiting as part of the Nuffield Department of Surgical Sciences Work Experience Programme. This annual programme offers school students aged ≥16 years a unique opportunity to gain valuable insight into careers in science and medicine, including time in the laboratory, shadowing clinicians and research nurses, a careers talk, and a feedback session.

It was a privilege to host the students for two afternoons. During their time with us, they learned about how QUOD samples are collected from organ donors at the 61 participating hospitals across the UK and then shipped to the QUOD hub in Oxford, where they are then processed and stored in the biobank. The students learned about the importance of the Human Tissue Act 2004 and were shown a video explaining the journey of a QUOD sample, from obtaining consent from the donor families to sample collection and storage in the biobank, as well as the types of research QUOD supports. They were then given a tour of our laboratory, where they watched a demonstration of how the samples that come to the Oxford hub are processed for long-term storage and how some of the tissue biopsies are processed as formalin-fixed paraffin-embedded blocks and subsequently sectioned using a microtome to prepare slides that go on to be used for histological analysis. The students also spent time with Dr Letizia Lo Faro from the Transplant Research Group, who uses QUOD samples in her research. They were given the opportunity to look at slides containing samples from different tissues (such as kidney, heart, and liver) under the microscope, see the types of equipment used for organ perfusion experiments, and gain hands-on experience practising their pipetting skills.

We wish the students every success for the future, whatever they go on to do, and hope that this experience has inspired them.

QUOD at TTS 2024

In September, QUOD travelled to Istanbul, Turkey, to attend The Transplantation Society 2024 (TTS2024) Congress. This was the first time that QUOD had participated at the biennial event, which enabled us to connect with a huge number of transplant professionals from across the world. It was a wonderful opportunity to catch up with QUOD colleagues as well as researchers who had used QUOD previously and were attending the congress. We had a lot of visitors and interest in our exhibition stand and we were able to promote the bioresource to a wide audience.

The TTS2024 programme was jam packed, with a wealth of novel research and new ideas being presented, sparking stimulating discussions. We were excited to see research using QUOD samples featured in an e-poster from Hussain Abbas. QUOD supplied samples from >1,000 liver donors to this study, which revealed differences between DBD and DCD donors and highlighted the under-utilisation of DCD livers as well as preretrieval biochemical and metabolic derangements that contribute to the risk factors associated with DCD livers.

TTS2024 was a huge success and opened up the opportunity to connect and showcase QUOD internationally.