QUOD at TTS 2024

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In September, QUOD travelled to Istanbul, Turkey, to attend The Transplantation Society 2024 (TTS2024) Congress. This was the first time that QUOD had participated at the biennial event, which enabled us to connect with a huge number of transplant professionals from across the world. It was a wonderful opportunity to catch up with QUOD colleagues as well as researchers who had used QUOD previously and were attending the congress. We had a lot of visitors and interest in our exhibition stand and we were able to promote the bioresource to a wide audience.

The TTS2024 programme was jam packed, with a wealth of novel research and new ideas being presented, sparking stimulating discussions. We were excited to see research using QUOD samples featured in an e-poster from Hussain Abbas. QUOD supplied samples from >1,000 liver donors to this study, which revealed differences between DBD and DCD donors and highlighted the under-utilisation of DCD livers as well as preretrieval biochemical and metabolic derangements that contribute to the risk factors associated with DCD livers.

TTS2024 was a huge success and opened up the opportunity to connect and showcase QUOD internationally.

Spotlight on a QUOD colleague – Karen Rockell

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For this issue of the QUOD newsletter, we caught up with Karen Rockell, Patient Co-Director of the UK Organ Donation and Transplantation Research Network (UKODTRN) and member of the QUOD Steering Committee.

Karen’s story of how she became involved with patient and public involvement and engagement (PPIE) in transplant research stemmed from her own first-hand experience as an organ recipient. Karen’s professional life began in business research, and she developed a wealth of knowledge working at Cranfield University for 10 years. However, her career took a different path when, in 2010, she became a liver transplant recipient, which prompted her to turn her focus towards health research. She recalled how she had always been interested in health research from an early age when her mother became a research participant for studies into a condition that she suffered from. Later, when Karen was diagnosed with an autoimmune condition, her interest in patient involvement in medical research was rekindled as she wanted to better understand her illness, explore possible new treatments, and be able to advocate for herself. After her transplant, she donated her “old” liver for research and, following her recovery, went on to join the NHS Blood and Transplant (NHSBT) public advisory group, thus beginning her journey in patient involvement in research.

Karen is Patient Co-Director of the UKODTRN, whose founding partners include NHSBT, the British Transplantation Society, and Kidney Research UK, who currently fund the network. The UKODTRN was initially set up to tackle some of the challenges presented by small, single-centre research that ultimately delay the time taken to generate results and increase knowledge. The UKODTRN aims to encourage collaboration and communication between researchers and support them to join forces and submit research applications as multicentre studies, which can generate larger datasets and overcome the geographical and other barriers that may prove problematic for single-centre studies. The UKODTRN sets out to involve patients right from the very beginning of the research, and the election of two co-directors, one clinician (Dr Adnan Sharif) and one patient (Karen Rockell), ensures a balance between and combines these two different but very relevant backgrounds. Karen’s role is to build the patient involvement group (PPIE), which now has around 160 members. The PPIE group includes waiting list and transplant patients, living donors, and donor families, as well as carers and families. There are also 140 clinicians, allied health professionals, scientists, research designers, and health economists.

The UKODTRN is currently focusing on two main projects, both of which are patient-driven and patient-centred. The first aims to identify research priorities and involves asking transplant patients and their carers what they think would improve patient outcomes. Once emerging themes have been identified, they will communicate with scientists to establish how to ask the right research questions to address these issues. The second project aims to demystify research, with the objective of developing a research-knowledge community to create plain-language summaries of research published within the past couple of years. These summaries will be written by patients, as those written by researchers may not be fully accessible to patients. These will take the form of written summaries, infographics, posters, leaflets, webinars, and podcasts to ensure that accessibility needs are met and the research is brought to patients in a really relatable way. The intention is to close the knowledge gap in order to share science with patients in a way that enables them to better understand their conditions and advocate for themselves.

Karen first heard about QUOD at the British Transplantation Society conference in Belfast, Northern Ireland in early March 2020, which, coincidentally, was when the UKODTRN was launched. QUOD had a stand at the conference and it was here that Karen first met Prof Rutger Ploeg, who told her about the work that QUOD was doing. This initial encounter led to discussions about future collaborations and Karen joining the QUOD Steering Committee. Within QUOD, Karen’s focus is on PPIE and transparency, in terms of QUOD ensuring that they communicate back to the transplant community about the research that is being supported by the biobank. While it can be challenging to communicate complex science in plain language, Karen feels it is crucial that patients are empowered by being able to access and understand the science. The UKODTRN plans to feature QUOD in their newsletter as well as a webinar to keep their audience updated and informed about QUOD’s work supporting research.

Karen feels that QUOD fills a great need by aiming to improve and increase our knowledge and understanding of organs and transplantation, for example, through the identification of biomarkers and the changes that occur from organ retrieval to transplantation and beyond. It is by understanding these changes that we can improve outcomes.

While a typical week for Karen is extremely varied, much of her time is spent speaking to patients about projects that have been presented to the UKODTRN, looking at requests to get involved with PPIE, interacting with researchers, and talking to collaborators and charities, as well as the strategic direction of the network.

In her spare time, Karen swims and will be representing Great Britain in the World Transplant Games in Dresden, Germany in 2025. She describes the Transplant Games as a really good example of how to get transplant recipients back to being a thriving person after years of being unwell, it is also an excellent opportunity to make friends and celebrate life and donors.

The QUOD team is hugely privileged and grateful to have Karen on board, as her lived experience as a transplant recipient and strong desire to make research accessible to all bring a fresh perspective. We look forward to working with Karen on future projects and wish her the best of luck for the World Transplant Games next year.

New QUOD Colleague Questionnaire – Michael Nation

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Michael Nation – Senior Development Advisor

What were you doing most recently before joining QUOD?

I was the Director of the National Unified Renal Translational Research Enterprise (NURTuRE).  In this role and working with a great team I helped to develop the first UK national centralised renal biobank, with cohorts in chronic kidney disease (CKD) and Idiopathic Nephrotic Syndrome (INS). I was also recently involved in the collaborative development of a new cohort in Acute Kidney Disease (AKD). 

What interested you about working with QUOD?

It’s heritage, the great team and its ambitious strategy to accelerate and “de-risk” research and ultimately game change patient outcomes on a UK and international basis. Plus, the challenge as there is a real need in this area.

What does your role involve?

Helping to develop plans that lead to new collaborations, increased funding, new infrastructure and a higher level of sample and data utilisation on a UK and international basis.

Lightning round time:

If you were stuck on an island what three things would you bring?

A piece of flint

A mirror to attract attention from a passing super yacht

Any Bear Grylls’ book

Where’s your favourite place?

Dancing a waltz on a tropical beach with my wife Helen

Finally, what kinds of enquiries should people bring to you, and how best can they reach you?

QUOD: opportunities for future collaboration, profiling and funding – mnation@successfuldevelopment.org

QUOD & Live Life Give Life

Jenny Collins News

Dr Luke Yates, trustee of the organ donation charity Live Life Give Life, introduces the work of the charity and the exciting new partnership with QUOD

Live Life Give Life is a small UK charity that raises awareness of organ donation and the transformative power of transplantation. We are run by volunteers, who are all affected personally by organ donation and from all perspectives of the transplant journey – as recipients, donors, and survivors of those lost waiting. One of our prime objectives is to encourage people to talk about organ donation with their families. Our work is carried out via awareness campaigns, events and activities, and initiatives such as The Orgamites characters, which have been created to help young children understand organ donation. We also fund small research projects that aim to improve the welfare of (and outcome for) patients who need transplants, and travel fellowships to foster collaborative research for early career researchers.

Live Life Give Life was founded in 2006 by Emily Thackray and Emma Harris both afflicted by cystic fibrosis (CF). The two young women had lost many friends to CF and, at the time, Emily was on the waiting list for a life-saving lung transplant. The shortage of organs and donors inspired Emily and Emma to create a T-shirt campaign to raise awareness and encourage people to sign the organ donor register. Live Life then Give Life was their slogan and their fledgling charity; and went on to attain charity status in 2008. Emily received a transplant is 2007, and a further transplant in 2014, but tragically passed soon after. Emma also received a transplant and continued to fundraise and raise awareness for the cause but very sadly passed away early this year.

In a new project, Live Life Give Life is partnering with QUOD to develop a unique pump-prime funding opportunity to aid transplant researchers utilise this fantastic biobank resource. Watch this space – further details of the grant and how to apply coming soon!

Website: livelifegivelife.org.uk  X: twitter.com/lltgl
Facebook: facebook.com/LLTGL  Instagram: instagram.com/livelifegivelifeuk/

Spotlight on a QUOD Colleague – Prof Colin Wilson

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For this issue of the QUOD newsletter, we caught up with Colin Wilson, Professor of Transplantation and Hepato–Pancreato–Biliary (HPB) Surgery at Newcastle University, NHS-employed Consultant Surgeon, and QUOD Principal Investigator for Newcastle. We spoke to Colin about his academic and clinical roles in transplantation as well as his role within the QUOD programme, including how QUOD is supporting the development of a novel artificial intelligence (AI)-informed assessment of organ quality.

In his role as QUOD Principal Investigator for Newcastle, Colin coordinates specimen collection and onward transport to Oxford. He works with various teams within the Newcastle-upon-Tyne Hospitals Trust; the HPB team delivers the QUOD boxes to Oxford and the organ retrieval team underpins this. Colin actively supports the professional development of his team members and encourages their involvement with QUOD.

Colin leads a team at the NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, which is a collaboration between Newcastle and Cambridge Universities. The programme involves clinical work and registry analyses to look at ways to improve organ utilisation and provide a scientific basis to develop policies in clinical practice around organ utilisation. The programme delivers work packages, protocols, projects, and trials. One such trial is OrQA (Organ Quality Assessment), which, in collaboration with QUOD, is developing a tool that uses AI-driven analysis of photographic images of organs (taken using devices such as smartphones) to predict their suitability for transplantation by assessing factors such as perfusion quality or percentage steatosis (in liver). Colin recalled his experiences as a child using his first camera, the rigmarole of taking the film to be developed, and the wait to receive the prints, whereas nowadays we all have very high-resolution cameras on our phones that could be applied to transform our approach to medicine. His enthusiasm for the use of technology to advance transplantation outcomes is clear and is just one of his visions for the future of transplantation.

Looking ahead, Colin is keen to support medical students aspiring to become transplant surgeons and is actively involved with the North East Surgical Training Academy (NESTAC) training and mentorship programme, which connects students and trainees with mentors. He considers himself to be extremely lucky to be able to support some of the very talented medical students who are interested in careers in transplant surgery. The pathway to becoming a consultant transplant surgeon begins with a one-year laboratory-based MRes project that is written up in a thesis and presented as oral and poster presentations, which may go on to be presented at conferences and meetings, followed by progression to academic foundation doctor (core training level), academic clinical fellow, and finally clinical lecturer. The programme takes around 10 years from start to finish and Colin is very much looking forward to seeing the first person “come off the conveyor belt”, who he first met as a medical student keen to become a consultant transplant surgeon. He has mentored and supported him throughout his career development and says “it is going to be a really big moment that I’m looking forward to”.

Colin’s own journey to become a transplant surgeon began in 1999, when he was working as a Senior House Officer on a gastroenterology ward with Oliver James, Professor of Hepatology, at the Freeman Hospital, Newcastle. It was here that he realised that liver transplantation was key to the successful treatment of many patients with liver ailments. In 2001, he began his PhD, supervised by Prof. David Talbot, on non-heart-beating kidney transplantation, which was novel and challenging work at the time. He then went on to complete his training as a Surgical Registrar from 2006–2012.

While transplant surgery can present challenges, Colin describes his job as rewarding and he is very much future-focused. He is driven by research, developing technology, and building strong teams, and most enjoys creating and delivering novel solutions to overcome (or work around) the hurdles and obstacles facing transplantation. His research aims to identify how to make the best use of the resources available, such as finding ways to overcome non-use of organs from deceased donors and achieve good long-term outcomes for patients, while prioritising safety. He is passionate about supporting the next generation of UK transplant surgeons, who will also face issues for patients with organ failure but may consider newer approaches such as the use of stem cells, AI, or xenotransplantation, which has been approved in the USA but is not currently implemented in the UK.

Colin is unquestionably proud of his hugely dedicated and committed team, comprising particularly talented members, all with broad-ranging areas of expertise and who have won numerous esteemed prizes for their work in transplantation, published cutting-edge research, and are developing “staggering” novel AI work. He mentors his team academically and it is hugely important to him to provide them with an environment in which they can flourish.

Colin describes the QUOD programme as “engaging and outward-looking”, and really values the focus it brings to transplant research. Of particular importance to him are the governance structures in place, in addition to the core biorepository work, as well as the fellowship among like-minded individuals who can build projects on top of the infrastructure that QUOD brings. “It’s not just what QUOD is, but what QUOD has allowed to build around it and the connections that has made it such a valuable resource for UK transplantation.” He believes that the UK is world-leading in many areas of transplantation and QUOD is at the core of that.

In addition to his work in Newcastle, Colin’s job sees him travelling to and presenting at national and international meetings. He will be co-chairing the ESOT Congress 2025 in London, which will focus on sustainability, not just in terms of climate emergency but also workforce and the issues and challenges facing the NHS and European healthcare systems that are struggling to deliver doctors, nurses, and specialists in transplantation.

While his work has taken him to various countries over the years, outside of his busy full-time clinical and academic roles, Colin cherishes time with his family, enjoying activities such as table tennis and travelling together, and is looking forward to a family holiday in the next few weeks.

Interviewed by Jenny Collins.

New QUOD Colleague Questionnaire – Dr Jenny Collins

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Dr Jenny Collins – Tissue Handling Technician & Communications Officer

What were you doing most recently before joining QUOD? 

I had two part-time jobs before I started with the QUOD team. I worked in publishing, as a Managing Editor of an endocrinology journal and as a copy editor, and I also worked in a secondary school as a Science Technician.  
 

What interested you about working with QUOD? 
As well as my background in publishing, I previously worked at the University of Oxford in research. This role appealed as it gives me the opportunity to bring together my lab skills and publishing experience in an organ transplantation setting, which is hugely interesting and will have an enormous positive impact on people’s lives.  

What does your role involve? 

I receive biopsy samples from various tissues (heart, kidney, liver, and ureter) and process them for histology. The formalin-fixed paraffin-embedded samples are then stored in the QUOD Biobank until they are requested for research. When the samples are required for research, I then cut sections and prepare slides for histological analysis.
I will also be involved in public engagement and communications to help to increase awareness and visibility of QUOD and the incredible impact the biobank can have on transplant research.

Lightning round time: 

If you were stuck on an island what three things would you bring? 

 A radio, a knife, and a great book.

Where’s your favourite place? 
It has to be the Hermitage of Braid and Blackford Hill in Edinburgh. I grew up in Edinburgh and have a lot of great memories of family walks here, including rolling eggs down Blackford Hill at Easter, which has also become a family tradition with my own children.

Finally, what kinds of enquiries should people bring to you, and how best can they reach you? 

Any questions about tissue processing or communications can be sent to me via email: jenny.collins@nds.ox.ac.uk.

Mr Mohamed Elzawahry, Clinical Research Fellow from the Oxford Transplant Centre at the University of Oxford, attended the BTS congress to present his work

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The British Transplantation Society (BTS) annual congress was held in Harrogate, UK from 6th to 8th March 2024. Additionally, on Tuesday 5th March, before the official start of the congress, there was a post-graduate masterclass that featured a set of very interesting talks around sustainability and organ offering for transplantation. The congress was focused on sustainability and resource management in transplantation, this was emphasized by the choice of plenary discussions and talks showcased throughout the 3 days.

Our group submitted a number of abstracts on our work using QUOD samples, which investigate multiple transplant related questions, and we were delighted to be invited to present in multiple oral sessions. Dr Sarah Cross presented an update on QUOD and highlighted some of the research studies that the biobank has supported in the Basic Science session ‘Combatting Ageing’ which was co-moderated by Dr Maria Kaisar. Later in the congress, Dr Ioannis Michelakis presented “Donor Cystatin-C association with posttransplant graft function” in the main auditorium in the ‘Clinical Oral Presentations’ session. Dr Sarah Fawaz presented “Circulating TNFα, TNFR1 and TNFR2 Levels in deceased donors negatively associate with posttransplant kidney function” in the ‘Basic & Translational Science Oral Presentations’ session. All of which stimulated very engaging and interesting discussions.

I was honoured to have my abstract, “Oxygenated hypothermic machine perfusion (HMPO2) of the pancreas; comparing a ‘continuous’ and an ‘end-ischaemic’ approach in a porcine circulatory death model,” invited to be presented at the prestigious ‘7 of the best’ session. This was the result of a challenging set of experiments which have now paved the way to ongoing work supported by the QUOD whole organ research initiative.

The congress hosted a delightful drinks reception at the end of the first day and later on a vibrant themed gala dinner celebrating World Book Day. Throughout the event, networking was easy and engaging around the many industry and partner booths, including the QUOD booth staffed by Dr Sarah Cross and Philippa Wren. Overall, the congress was a great success, with excellent talks covering a wide range of multi-disciplinary interesting topics under the guise of transplantation.

QUOD’s British Transplantation Society (BTS) 2024 Overview

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QUOD attended the BTS Congress in Harrogate from 6-8 March. The annual congress brought together over 500 attendees and from our exhibition stand we were able to meet and connect with researchers, nurses, surgeons and clinicians, as well as charity and industry representatives and NHSBT staff in a wide variety of roles. Having the opportunity to talk to so many people involved in the QUOD programme from across the UK, as well as researchers who have previously or are currently using QUOD samples was so valuable. We were also able to raise awareness of the bioresource and highlight its value to potential future users.

QUOD had a large presence throughout the congress. In the ‘Diversity in Transplantation’ session, QUOD Steering Committee members Colin Wilson and Isabel Quiroga debated for and against ‘Women in Transplant: There are barriers to progressing in transplant surgery’. In the same session Menna Clatworthy, whose group at the University of Cambridge have received QUOD samples for a few research projects, participated in the panel discussion on ‘Socioeconomic, gender and ethnic diversity’. In the Basic Science session on ‘Combating aging’, QUOD National Operational Coordinator Sarah Cross presented an update on QUOD activity and highlighted some exciting work from several QUOD supported research projects in the area of organ aging.

Research using QUOD samples was presented in a number of presentations during the congress. In the prestigious Medawar Medal session, Stephanie Chong from UCL presented her work ‘Composition of the neutralising antibody response predicts risk of BK virus viraemia in renal transplant recipients’. QUOD has supplied Stephanie with donor serum and spleen samples to help facilitate this project and it was terrific to see the results being showcased in this notable session. Two biomarker studies in kidney transplantation which used QUOD donor plasma samples were presented by researchers from the University of Oxford. In the ‘Clinical Oral presentations’ session Ioannis Michelakis talked about his study ‘Donor Cystatin-C association with post-transplant graft function’. In the ‘Basic and Translational Science Oral presentations’ session Sarah Fawaz presented her work ‘Circulating TNFα, TNFR1 and TNFR2 Levels in deceased donors negatively associate with posttransplant kidney function’. In the ‘Calne Williams Medal presentations’ session, the latest developments from the OrQA project, of which QUOD is a collaborative partner, were presented by Georgious Kourounis from Newcastle University ‘Organ Quality Assessment for Livers (OrQA-L): Real-time visual assessment of steatosis during retrieval using machine learning models’.

As is BTS tradition, the gala dinner for this year’s congress had a theme, and due to it falling on World Book Day, delegates arrived dressed up as fictional characters ranging from Moby Dick, Gandalf and the Hobbit and Red Riding Hood, to a swarm of Where’s Wallys! It was a hugely enjoyable evening that ended with us dancing the night away on a packed dance floor to a particularly good live band.

We would like to thank BTS for its continued support and look forward to the 2025 congress where we can showcase more of our scientific collaborations and impact.

QUOD Whole Organ Expansion

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In 2018, a multi-disciplinary team of researchers from Oxford and Newcastle, led by Professor Rutger Ploeg and Professor James Shaw, was awarded a grant of £1.7 million from the Medical Research Council (MRC) to enable the expansion of QUOD to establish a whole organ tissue bank.

This funding enabled the central QUOD clinical data, blood / urine sample and tissue biopsy Bioresource in Oxford to be augmented by systematic processing of whole organ pancreas, heart and lungs from deceased organ donors to collect anatomically-driven mutimodal biopsies. This grant allowed QUOD to establish cross-cutting scientific platforms including state-of-the-art pathology, transcriptomics, proteomics and light / multiplex fluorescence / EM imaging. The QUOD-PANC tissue bank at Newcastle University has archived samples from 120 donors within a searchable online Atlas comprising from normal, ischaemic and chronically diseased pancreata. Underlying pathologies include type 1, type 2 and type 3c diabetes in addition to chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN).

About QUOD Whole Organ Resource

The QUOD whole organ expansion programme at Newcastle University is coordinated by scientists and clinicians including Professors James Shaw, Andrew Fisher, John Dark, Dina Tiniakos and Dr Bill Scott. Quality-assured tissue processing is undertaken by dedicated biomedical scientists led by Minna Honkanen-Scott within the Transplant Regenerative Medicine Laboratories at the International Centre for Life. Professor Paul Johnson leads a parallel research pancreatic islet isolation programme at the University of Oxford.

QUOD Expand facilitates integration of high-quality clinical data, circulating biomarkers and deep molecular phenotyping towards deeper understanding of the stresses associated with organ donation and transplantation together with the mechanisms underlying tissue pathologies. The overall goal is development of novel therapeutic strategies to optimise organ transplantation, tissue replacement therapy and in situ endogenous tissue repair.

(H&E stained image of an islet. 40x magnification)

Following dissection from surrounding tissue, the whole organ is assessed and photographed macroscopically before collection of multimodal biopsies from anatomically defined regions. Light microscopy images are obtained following a standard suite of dye and immunohistochemical stains for clinical pathologist assessment and Artificial Intelligence-driven image analysis (led by Professor Sarah Richardson, Exeter University). Standardised ultrastructural assessment by transmission electron microscopy has been validated.

The whole organ expansion programme has benefitted significantly from an NHSBT initiative Increasing the Number of Organs Available for Research (INOAR) which has included pancreata from donors with diabetes.

The QUOD expansion programme is aligned to the overall QUOD mission: ‘Saving lives and cutting health care costs by increasing the pool of transplantable organs, thereby addressing the growing gap between supply and demand in organ transplantation’ and provides a powerful new resource for disease-specific research.

QUOD Panc Atlas

An online Portal is in development providing access to a library comprising donor data; organ / tissue images; AI analysis; and a catalogue of samples available for research within the Quality in Organ Donation whole organ human pancreas tissue bank – QUOD-PANC.

The goal is to establish, curate and share a unique Bioresource representing the range of normality, acute stress and chronic disease within human pancreas – in parallel with access to detailed donor clinical data and quality-assured clinical pathologist reporting.

Integration with the core QUOD Biobank enables parallel access to donor circulating blood and urine samples in addition to small biopsies from other tissues.

The Portal provides access to organ donor clinical data in parallel with macroscopic and microscopic pancreas images. Multimodal samples from each anatomically defined region (8 in total from head to tail of pancreas) comprise: Formalin Fixed Paraffin Embedded tissue blocks (anterior and posterior) / snap-frozen tissue blocks / bulk protein samples / RNAlater samples / glutaraldehyde-fixed samples for EM. Sample details are catalogued for each donor.

Initial requests can be made through the Portal for samples to be processed centrally or released for approved research.

Researchers wishing to access QUOD samples should submit a preliminary registration online for Administrator approval and if successful submit a relevant project for review.

Contact us at atlasportal@ncl.ac.uk

For further information on the work being undertaken in Newcastle please go to Regenerative Medicine, Stem Cells, Transplantation | Faculty of Medical Sciences | Newcastle University (ncl.ac.uk)       

New QUOD Colleague Questionnaire – Kerry Clare

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Kerry Clare – Oxford Transplant Biobank (OTB) Coordinator & QUOD Oxford Regional Operational Coordinator

What were you doing most recently before joining QUOD and OTB?

I was working within the Oncology & Haematology department at the Churchill Hospital, Oxford as a Clinical Coordinator.

What interested you about working with QUOD and OTB?
I have previous experience with haematology and lab work and thought a role within a research biobank sounded interesting and rewarding.

What does your role involve?
I am the Senior Biobank Coordinator for OTB & QUANTUM biobanks and the Regional Operational Coordinator for the Oxford region for QUOD. I retrieve and process donor samples, ensure accurate entry of details into the respective biobank databases and am responsible for the smooth running of the sample collection and storage process.

Lightning round time:

If you were stuck on an island what three things would you bring?

My dogs, a fishing net and matches.

Where’s your favourite place?
Cornwall – many memorable family holidays.

Finally, what kinds of enquiries should people bring to you, and how best can they reach you?

Any sample collection and/or processing enquiries for OTB, QUOD and QUANTUM biobanks. Email kerry.clare@nds.ox.ac.uk.