Organ donation and transplant saves thousands of lives a year and could be considered one of the greatest successes in modern medicine. However, over the past decade, there has been an ever increasing need for organs throughout the UK, far surpassing the supply. This is a pattern that is predicted to worsen over the next 10 years.
As many as one in three patients on the transplant waiting list will die or become too unwell to receive a transplant as a result of this disparity.
To address this problem, the transplant community have been turning to organs previously considered to be unsuitable for transplantation, including organs from extended criteria donors and non-heart beating donors. In order to do this, QUOD aims to facilitate research by collecting blood, urine and tissue samples of appropriately consented / authorised organ donors. Through this, it may be possible to determine pathways of injury and repair in organs and identify biomarkers which can be used to better predict the outcomes of transplantation.
QUOD is a nationwide programme encompassing all retrieval zones in the UK. These regions include:
The QUOD team has a wide range of personnel, including specialist nurses, transplant surgeons, academics, management teams and a variety of healthcare professionals. To see more about the team involved with QUOD, click here.
The samples collected throughout the QUOD programme are available for research purposes. Samples will be available to research projects based on scientific merit. More information about the access policy can be found here.
In QUOD samples are taken for QUOD in accordance with the Human Tissue Act 2004 or the Human Tissue (Scotland) Act 2006. Outside of Scotland the samples must be taken under a licence from the Human Tissue Authority. NHSBT holds a Research licence (HTA licence number 12608) which is site specific and covers their Dedicated Donation Facility at Speke in Liverpool. The NHSBT Designated Individual for this licence is Ian Bateman, Director of Quality. To allow samples to be taken for QUOD the Human Tissue Authority has extended this licence to include areas in 41 hospitals as ‘satellite sites’. The satellite site licences for NHSBT Research licence can ONLY be used for the removal of approved samples for QUOD. This solution assumes that the NHSBT Designated Individual takes personal responsibility for the extended licence, including the practices and people working under the licence. The Person Designate for each National Organ Retrieval Service (NORS) team is Fidelma Murphy, NHSBT National Quality Manager, and for the SNOD/Organ Donation Service Teams (ODST) the team Regional Manager.